At the crossroads of West Africa and Central Africa, the territory of what is now Cameroon has seen human habitation since some time in the Middle Paleolithic, likely no later than 130,000 years ago. The earliest discovered archaeological evidence of humans dates from around 30,000 years ago at Shum Laka. The Bamenda highlands in western Cameroon near the border with Nigeria are one of the most likely origin for the Bantu peoples, whose language and culture came to dominate most of central and southern Africa between 1000 BCE and 1000 CE.

European traders arrived in the fifteenth century and Cameroon was the exonym given by the Portuguese to the Wouri River, which they called Rio dos Camarões—"river of shrimps" or "shrimp river", referring to the then-abundant Cameroon ghost shrimp.Cameroon (adj.) Cameroon was a source of slaves for the slave trade. While the northern part of Cameroon was subject to influence from the Islamic kingdoms in the Chad basin and the Sahel, the south was largely ruled by small kings, chieftains, and fons.

Cameroon as a political entity emerged from the colonization of Africa by Europeans. From 1884, Cameroon was a German colony, German Kamerun, with its borders drawn through negotiations between the Germans, British, and French. After the First World War, the League of Nations mandated France to administer most of the territory, with the United Kingdom administering a small portion in the west. Following World War II, the League of Nations' successor, the United Nations, instituted a Trusteeship system, leaving France and Britain in control of their respective regions, French Cameroon and British Cameroon. In 1960, Cameroon became independent with part of British Cameroons voting to join former French Cameroon. Cameroon has had only two presidents since independence and while opposition parties were legalized in 1990 only one party has ever governed. Cameroon has maintained close relations with France and allied itself largely with Western political and economic interests throughout the Cold War and into the twenty-first century. This consistency gave Cameroon a reputation as one of the most stable countries in the region. In 2017, tensions between Anglophone Cameroonians in former British territory and the Francophone-dominated government led to an ongoing civil war known as the Anglophone Crisis in the west of the country, while Islamist insurgents Boko Haram continue to carry out military and terror attacks in the north of the country.

In January 2024, Cameroon launched the world's first routine malaria vaccine program, using the World Health Organization (WHO)-approved RTS,S vaccine developed by British drugmaker GSK. The initiative aims to save thousands of African children's lives annually. Despite some skepticism, health experts emphasize careful community outreach to combat vaccine hesitancy and stress the importance of using existing preventive measures alongside vaccines.

Pre-colonial history Prehistory

Archaeological research has been relatively scarce in Cameroon due to a lack of resources and transportation infrastructure. Historically the warm, wet climate in many parts of the country was thought of as inhospitable to the preservation of remains, but recent finds and the introduction of new techniques have challenged that assumption. Evidence from digs at Shum Laka in the Northwest Region shows human occupation dating back 30,000 yearsLavachery, Philippe (2001) The Holocene Archaeological Sequence of Shum Laka Rock Shelter (Grasslands, Western Cameroon). African Archaeological Review 18(4):213-247.Cornelissen, Els (2003) On Microlithic Quartz Industries at the End of the Pleistocene in Central Africa: The Evidence from Shum Laka (NW Cameroon). African Archaeological Review 20(1):1-24. while in the dense forests of the south, the oldest evidence of occupation is around 7000 years old. Recent research in southern Cameroon indicates that the Iron Age may have started there as early as 1000 BCE and was certainly well established by 100 BCE at the latest.

Linguistic analysis, supported by archaeological and genetic research, has shown that the Bantu expansion, a series of migrations that spread Bantu culture across much of Sub-Saharan Africa, most likely originated in the highlands on the Nigeria-Cameroon border around 1000 BCE. Bantu languages spread with these people along with agricultural methods and possibly iron tools, first east and then south, forming one of the largest language families in Africa. In Cameroon, Bantu people largely displaced Central African Pygmies such as the Baka, who were hunter-gatherers and who now survive in much smaller numbers in the heavily forested southeast. Despite Cameroon being the original homeland of the Bantu people, the great medieval Bantu-speaking kingdoms arose elsewhere, such as what is now Kenya, Congo, Angola, and South Africa.

Northern Cameroon The earliest known civilization to have left clear traces of their presence in the territory of modern Cameroon is known as the Sao civilisation. Known for their elaborate terracotta and bronze artwork and round, walled settlements in the Lake Chad Basin, little else is known with any certainty due to the lack of historical records. The culture possibly arose as early as the fourth century BC but certainly, by the end of the first millennium BC, their presence was well established around Lake Chad and near the Chari River. The city-states of the Sao reached their apex sometime between the ninth and fifteenth centuries AD. The Sao were displaced or assimilated by the sixteenth century.

After the Muslim conquest of North Africa in 709, Islam's influence began to spread south with the growth of trans-Saharan trade, including in what is now northern Cameroon. The Kanem-Bornu Empire began in what is now Chad and likely came into conflict with the Sao. The Kanem Empire began in Chad in the eighth century and gradually extended its influence northward into Libya and southward into Nigeria and Cameroon. Slaves from raids in the south were their principal trade good along with mined salt. The Empire was Muslim from at least the eleventh century and reached its first peak in the 13th, controlling most of what is now Chad and smaller regions in surrounding countries. After a period of internal instability, the center of power shifted to Bornu with its capital at Ngazargamu, in what is now northwestern Nigeria, and territory was gradually reconquered and new territory in present-day Niger also conquered. The Empire began to decline in the seventeenth century though it continued to control much of northern Cameroon.

From 1804 to 1808 the Fulani War saw the Bornu pushed north out of Cameroon and the Sokoto Caliphate took control of the region, as well as most of northern Nigeria and large swathes of Niger and Mali. A feudal empire with local rulers pledging allegiance and paying tributes to the Caliph, northern Cameroon was likely part of the Adamawa Emirate within the Caliphate. This structure proved susceptible to exploitation by colonial powers beginning in the 1870s, who sought to undermine local rulers' ties to the Caliphate.

Southern Regions The Muslim empires of the Sahara and Sahel never reached further south than the highlands of the Cameroon Line. Further south, there is little archaeological evidence of large empires or kingdoms and no historical record due to the lack of writing in the region. When the Portuguese arrived in the region in the fifteenth century, a large number of kings, chiefs, and fons ruled small territories. Many ethnic groups, particularly speakers of the Grassfields languages in the west, have oral histories of migrating south fleeing Muslim invaders, likely reference to the Fulani War and subsequent conflicts in Nigeria and northern Cameroon.

Malaria prevented significant European settlement or exploration until the late 1870s, when large supplies of the malaria suppressant quinine became available. The early European presence in Cameroon was primarily devoted to coastal trade and the acquisition of slaves. The Cameroon coast was a major hub for the purchase of slaves who were taken across the Atlantic to Brazil, the United States, and the Caribbean. In 1807, the British abolished slavery in the Empire and began military efforts to suppress the slave trade, particularly in West Africa. Combined with the end of legal slave imports in the United States the same year, the international slave trade in Cameroon declined sharply. Christian missionaries established a presence in the late nineteenth century. Around this time, the Aro Confederacy, was expanding its economic and political influence from southeastern Nigeria into western Cameroon. However, the arrival of British and German colonizers cut short its growth and influence.

Colonial period

Scramble for Africa and German Kamerun (1884–1918)

The Scramble for Africa beginning in the late 1870s, saw European powers, primarily seeking to establish formal control over the parts of Africa not yet colonized. The Cameroon coast was of interest to both the British, already established in what is now Nigeria and with missionaries outposts in several towns, and the Germans who had extensive trading relationships and plantations established in the Douala region. On July 5, 1884, German explorer and administrator Gustav Nachtigal began signing agreements with Duala leaders establishing a German protectorate in the region. A brief conflict ensued with rival Duala chiefs which Germany and its allies won, leaving the British with little choice but to acknowledge Germany's claim to the region. The borders of modern Cameroon were established through a series of negotiations with the British and French. Germany established an administration for the colony with a capital first at Buea and later at Yaoundé and continued to explore the interior and co-opt or subjugate local rulers. The largest conflicts were the Bafut Wars and the Adamawa Wars which ended by 1907 with German victories.

Germany was particularly interested in Cameroon's agricultural potential and entrusted large firms with the task of exploiting and exporting it. German Chancellor Otto von Bismarck defined the order of priorities as follows: "first the merchant, then the soldier". It was under the influence of a businessman Adolph Woermann, whose company set up a trading house in Douala, that Bismarck, initially skeptical about the interest of the colonial project, was convinced. Large German trading companies (Woermann, Jantzen & Thormählen) and concession companies (Südkamerun Gesellschaft, Nord-West Kamerun Gesellschaft) established themselves massively in the colony. Letting the big companies impose their order, the administration simply supported them, protected them, and tried to eliminate indigenous rebellions.The Imperial German government made substantial investments in the infrastructure of Cameroon, including the extensive railways, such as the 160-metre single-span railway bridge on the southern branch of Sanaga River. However, the indigenous peoples proved reluctant to work on these projects, so the Germans instigated a harsh and unpopular system of forced labour.DeLancey and DeLancey 125. In fact, Jesko von Puttkamer was relieved of duty as governor of the colony due to his untoward actions toward the native Cameroonians.DeLancey and DeLancey 226. In 1911 at the Treaty of Fez after the Agadir Crisis, France ceded a nearly 300,000 km2 portion of the territory of French Equatorial Africa to Kamerun which became Neukamerun (New Cameroon), while Germany ceded a smaller area in the north in present-day Chad to France.