Searles is a surname. Notable people with the surname include:

A. Langley Searles (1920–2009), American chemist Adam Searles (born 1981), British actor Baird Searles (1934–1993), American science fiction author and critic Charles Searles (1937–2004), American artist Colbert Searles (1873–1947), American college football coach DeWitt Searles (1920–2021), American Air Force major general Edward Francis Searles (1841–1920), American architect Helen McGaffey Searles (1856–1936), American professor, classicist, and women's suffragist Harold Searles (1918–2015), American psychiatrist Javon Searles (born 1986), Barbadian cricketer John Searles, American author and magazine editor Joseph L. Searles III (1942–2021), American stockbroker Mary Hopkins Searles (1818–1891), American businesswoman Michael Searles (1750–1813), English architect Robert L. Searles (1919–2004), American businessman and politician

See also Searle (surname)