Ayşe Sultan or Ayşe Hatun may refer to:
People Ayşe Sultan (daughter of Bayezid II) (c. 1465 – c. 1515) Ayşe Gülbahar Hatun (mother of Selim I) (c. 1453 – c. 1505), concubine of Bayezid II Ayşe Hafsa Sultan (1478/1479 – 1534), concubine of Sultan Selim I, mother of Suleiman the Magnificent Ayşe Hatun (consort of Selim I) (c. 1476 – 1539) Ayşe Hümaşah Sultan (1541 – c. 1589), daughter of Mihrimah Sultan Ayşe Sultan (daughter of Murad III) (1565–1605) Ayşe Sultan (daughter of Ahmed I) (c. 1605 – 1657) Ayşe Sultan (Haseki of Osman II) (c. 1607 – c. 1640) Ayşe Sultan (Haseki of Murad IV) (died c. 1680) Ayşe Sultan (daughter of Mustafa II) (1696–1752), also called Büyük Ayşe Ayşe Sultan (daughter of Ahmed III) (1715–1776), also called Küçuk Ayşe Ayşe Sultan (daughter of Abdul Hamid II) (1887–1960), also called Ayşe Osmanoğlu
Fictional characters Ayşe Hatun, a Kuruluş: Osman character
See also Aisha Sultan Begum, Timurid princess and Mughal queen