S300 may refer to:
Military and aviation S-300 missile system, a Soviet/Russian surface-to-air missile system HNoMS Ula (S300), a Royal Norwegian Navy submarine Schweizer 300, formerly Sikorsky S300, a family of light utility helicopters
Other uses Canon PowerShot S300, a camera Lotus Esprit S300, a car Mercedes-Benz S-300, a car S300, a Sendo mobile phone model S300, a Victorian Railways S class steam locomotive of Australia
See also
300 (disambiguation) 300s (disambiguation) 300 series (disambiguation), including Series 300